Anti-caspase-3 preconditioning increases proinsulin secretion and deteriorates posttransplant function of isolated human islets

<p style="text-align:justify;"> Human islet isolation is associated with adverse conditions inducing apoptosis and necrosis. The aim of the present study was to assess whether antiapoptotic preconditioning can improve in vitro and posttransplant function of isolated human islets. A...

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Detalles Bibliográficos
Main Authors: Brandhorst, D, Brandhorst, H, Maataoui, V, Maataoui, A, Johnson, P
Formato: Journal article
Idioma:English
Publicado: Springer 2013