An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns

Rho GTPase-based signaling networks control cellular dynamics by coordinating protrusions and retractions in space and time. Here, we reveal a signaling network that generates pulses and propagating waves of cell contractions. These dynamic patterns emerge via self organization from an activator-inh...

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Main Authors: Graessl, M, Koch, J, Calderon, A, Kamps, D, Banerjee, S, Mazel, T, Schulze, N, Jungkurth, J, Patwardhan, R, Solouk, D, Hampe, N, Hoffmann, B, Dehmelt, L, Nalbant, P
格式: Journal article
出版: Rockefeller university Press 2017