The chemical synthesis, stability, and activity of MAIT cell prodrug agonists that access MR1 in recycling endosomes

The chemical synthesis, stability, and activity of MAIT cell prodrug agonists that access MR1 in recycling endosomes

Mucosal-associated invariant T (MAIT) cells are antibacterial effector T cells that react to pyrimidines derived from bacterial riboflavin synthesis presented by the monomorphic molecule MR1. A major challenge in MAIT cell research is that the commonly used MAIT agonist precursor, 5-amino-6-d-ribity...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Lange, J, Anderson, R, Marshall, A, Chan, S, Bilbrough, T, Gasser, O, Gonzalez-Lopez, C, Salio, M, Cerundolo, V, Hermans, I, Painter, G
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	American Chemical Society 2020

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