The chemical synthesis, stability, and activity of MAIT cell prodrug agonists that access MR1 in recycling endosomes

The chemical synthesis, stability, and activity of MAIT cell prodrug agonists that access MR1 in recycling endosomes

Mucosal-associated invariant T (MAIT) cells are antibacterial effector T cells that react to pyrimidines derived from bacterial riboflavin synthesis presented by the monomorphic molecule MR1. A major challenge in MAIT cell research is that the commonly used MAIT agonist precursor, 5-amino-6-d-ribity...

書誌詳細
主要な著者:	Lange, J, Anderson, R, Marshall, A, Chan, S, Bilbrough, T, Gasser, O, Gonzalez-Lopez, C, Salio, M, Cerundolo, V, Hermans, I, Painter, G
フォーマット:	Journal article
言語:	English
出版事項:	American Chemical Society 2020

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