The pathogenesis of the bone disease of multiple myeloma.

Multiple myeloma is a fatal hematologic malignancy associated with clonal expansion of malignant plasma cells within the bone marrow and the development of a destructive osteolytic bone disease. The principal cellular mechanisms involved in the development of myeloma bone disease are an increase in...

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Bibliographic Details
Main Authors: Edwards, C, Zhuang, J, Mundy, G
Format: Journal article
Language:English
Published: 2008