The pathogenesis of the bone disease of multiple myeloma.
Multiple myeloma is a fatal hematologic malignancy associated with clonal expansion of malignant plasma cells within the bone marrow and the development of a destructive osteolytic bone disease. The principal cellular mechanisms involved in the development of myeloma bone disease are an increase in...
Main Authors: | Edwards, C, Zhuang, J, Mundy, G |
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Format: | Journal article |
Language: | English |
Published: |
2008
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