The pathogenesis of the bone disease of multiple myeloma.

Multiple myeloma is a fatal hematologic malignancy associated with clonal expansion of malignant plasma cells within the bone marrow and the development of a destructive osteolytic bone disease. The principal cellular mechanisms involved in the development of myeloma bone disease are an increase in...

Полное описание

Библиографические подробности
Главные авторы: Edwards, C, Zhuang, J, Mundy, G
Формат: Journal article
Язык:English
Опубликовано: 2008