Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens
<p><strong>Background:</strong> In humans and other animals, the chronic hypoxic response is mediated by hypoxia inducible transcription factors (HIFs) which regulate the expression of genes that counteract the effects of limiting oxygen. Prolyl hydroxylases (PHDs) act as hypoxia s...
| Principais autores: | , , , , , , , |
|---|---|
| Formato: | Journal article |
| Publicado em: |
Dove Medical Press
2018
|