G . T base-pairs in a DNA helix: the crystal structure of d(G-G-G-G-T-C-C-C).

The synthetic deoxyoctanucleotide d(G-G-G-G-T-C-C-C) crystallizes as an A-type DNA double helix containing two adjacent G . T base-pair mismatches. The structure has been refined to an R-factor of 14% at 2.1 A resolution with 104 solvent molecules located. The two G . T mismatches adopt the "wo...

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Bibliographic Details
Main Authors: Kneale, G, Brown, T, Kennard, O, Rabinovich, D
Format: Journal article
Language:English
Published: 1985