Visualizing dynamic microvillar search and stabilization during ligand detection by T cells.

During immune surveillance, T cells survey the surface of antigen-presenting cells. In searching for peptide-loaded major histocompatibility complexes (pMHCs), they must solve a classic trade-off between speed and sensitivity. It has long been supposed that microvilli on T cells act as sensory organ...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Cai, E, Marchuk, K, Beemiller, P, Beppler, C, Rubashkin, MG, Weaver, VM, Gérard, A, Liu, TL, Chen, BC, Betzig, E, Bartumeus, F, Krummel, MF
Μορφή: Journal article
Γλώσσα:English
Έκδοση: American Association for the Advancement of Science 2017