Visualizing dynamic microvillar search and stabilization during ligand detection by T cells.

During immune surveillance, T cells survey the surface of antigen-presenting cells. In searching for peptide-loaded major histocompatibility complexes (pMHCs), they must solve a classic trade-off between speed and sensitivity. It has long been supposed that microvilli on T cells act as sensory organ...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Cai, E, Marchuk, K, Beemiller, P, Beppler, C, Rubashkin, MG, Weaver, VM, Gérard, A, Liu, TL, Chen, BC, Betzig, E, Bartumeus, F, Krummel, MF
التنسيق: Journal article
اللغة:English
منشور في: American Association for the Advancement of Science 2017