Dissecting the pathobiology of altered MRI signal in amyotrophic lateral sclerosis: A post mortem whole brain sampling strategy for the integration of ultra-high-field MRI and quantitative neuropathology

Amyotrophic lateral sclerosis (ALS) is a clinically and histopathologically heterogeneous neurodegenerative disorder, in which therapy is hindered by the rapid progression of disease and lack of biomarkers. Magnetic resonance imaging (MRI) has demonstrated its potential for detecting the pathologica...

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Detalles Bibliográficos
Main Authors: Pallebage-Gamarallage, M, Foxley, S, Menke, R, Huszar, I, Jenkinson, M, Tendler, B, Wang, C, Jbabdi, S, Turner, M, Miller, K, Ansorge, O
Formato: Journal article
Idioma:English
Publicado: BioMed Central 2018