Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children.

The highly sensitive quantitation of virus-specific CD8(+) T cells using major histocompatibility complex-peptide tetramer assays has revealed higher levels of cytotoxic T lymphocytes (CTLs) in acute and chronic virus infections than were recognized previously. However, studies in lymphocytic chorio...

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Bibliographic Details
Main Authors: Goulder, P, Tang, Y, Brander, C, Betts, MR, Altfeld, M, Annamalai, K, Trocha, A, He, S, Rosenberg, E, Ogg, G, O'Callaghan, C, Kalams, SA, McKinney, R, Mayer, K, Koup, R, Pelton, S, Burchett, S, McIntosh, K, Walker, B
Format: Journal article
Language:English
Published: 2000