Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters

Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters

Biotin is an essential vitamin in plants and mammals, functioning as the carbon dioxide carrier within central lipid metabolism. Bacterial pimeloyl-CoA synthetase (BioW) acts as a highly specific substrate-selection gate, ensuring the integrity of the carbon chain in biotin synthesis. BioW catalyzes...

书目详细资料
Main Authors:	Wang, M, Moynié, L, Harrison, P, Kelly, V, Piper, A, Naismith, J, Campopiano, D
格式:	Journal article
语言:	English
出版:	Springer Nature 2017

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