Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein.

The cDNA for one of the receptors for human tumor necrosis factor (TNF) has been isolated. This cDNA encodes a protein of 455 amino acids that is divided into an extracellular domain of 171 residues and a cytoplasmic domain of 221 residues. The extracellular domain has been engineered for expression...

Full description

Bibliographic Details
Main Authors: Gray, P, Barrett, K, Chantry, D, Turner, M, Feldmann, M
Format: Journal article
Language:English
Published: 1990