Pyrrolidinones derived from (S)-pyroglutamic acid. Part 3. beta-aminopyrrolidinones
The conjugate addition of activated nitrogen nucleophiles, such as hydroxylamine and hydrazine derivatives, to α, β-unsaturated bicyclic lactam 1a gave the corresponding β-amino products 9a-g in good yield and excellent diastereo- selectivity. These products can be manipulated to afford enantiopure...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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