Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria.

Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria.

BACKGROUND: Currently, population pharmacokinetic (PK) studies of anti-malarial drugs are designed primarily by the logistical and ethical constraints of taking blood samples from patients, and the statistical models that are fitted to the data are not formally considered. This could lead to impreci...

Полное описание

Библиографические подробности
Главные авторы:	Jamsen, K, Duffull, S, Tarning, J, Lindegardh, N, White, N, Simpson, J
Формат:	Journal article
Язык:	English
Опубликовано:	BioMed Central 2011

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