T cell antigen receptor signaling and immunological synapse stability require myosin IIA.

Immunological synapses are initiated by signaling in discrete T cell antigen receptor microclusters and are important for the differentiation and effector functions of T cells. Synapse formation involves the orchestrated movement of microclusters toward the center of the contact area with the antige...

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Bibliographic Details
Main Authors: Ilani, T, Vasiliver-Shamis, G, Vardhana, S, Bretscher, A, Dustin, M
Format: Journal article
Language:English
Published: 2009