Paradoxical effects of adenovirus-mediated blockade of TNF activity in murine collagen-induced arthritis.

Collagen-induced arthritis (CIA) is an experimental model of arthritis widely used to dissect the pathogenesis of human rheumatoid arthritis and to identify potential therapeutic targets. Among these, TNF-alpha has been recognized to play an important role. Here we investigate the feasibility and th...

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Bibliographic Details
Main Authors: Quattrocchi, E, Walmsley, M, Browne, K, Williams, R, Marinova-Mutafchieva, L, Buurman, W, Butler, D, Feldmann, M
Format: Journal article
Language:English
Published: 1999