Role of cholesterol metabolism in the anticancer pharmacology of selective estrogen receptor modulators

Selective estrogen receptor modulators (SERMs) are a class of compounds that bind to estrogen receptors (ERs) and possess estrogen agonist or antagonist actions in different tissues. As such, they are widely used drugs. For instance, tamoxifen, the most prescribed SERM, is used to treat ERα-positive...

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Bibliographic Details
Main Authors: Gómez-Coronado, D, Lasunción, MA, Martínez-Botas, J, Fernandez-Suarez, ME
Format: Journal article
Language:English
Published: Elsevier 2020