Genetic and molecular basis of myeloid neoplasms at single cell resolution
<p>Myeloproliferative neoplasms (MPN) originate in a single human haematopoietic stem cell which acquires a somatic mutation and undergoes clonal expansion. This initial clone usually accumulates further genetic lesions during disease progression, giving rise to a genetically heterogeneous po...
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| Format: | Thesis |
| Language: | English |
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2019
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