Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy.

To be able to detect in situ changes in protein conformation without perturbing the physiological environment would be a major step forward in understanding the precise mechanism occurring in protein interaction. We have developed a novel approach to monitoring conformational changes of proteins in...

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Bibliografische gegevens
Hoofdauteurs: Calleja, V, Ameer-Beg, S, Vojnovic, B, Woscholski, R, Downward, J, Larijani, B
Formaat: Journal article
Taal:English
Gepubliceerd in: 2003