Ameliorating β-thalassaemia by manipulating expression of the α-globin gene

<p>β-Thalassaemia is a disorder of haemoglobin production characterised by severe anaemia requiring life-long blood transfusions. The common genetic defects are predominantly based in and around the β-globin gene resulting in reduced or absent β-globin chain synthesis. The resultant excess of...

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Bibliographic Details
Main Author: Mettananda, S
Other Authors: Higgs, D
Format: Thesis
Language:English
Published: 2015
Subjects: