Normoxic cells remotely regulate the acid-base balance of cells at the hypoxic core of connexin-coupled tumor-growths

A significant proportion of ATP fuels the removal of metabolic end-products, particularly H+ ions which profoundly affect biological activities. Since energetic resources in hypoxic tumor-regions are constrained by low-yielding glycolysis, any means of reducing the cost of acid-extrusion, without co...

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Bibliographic Details
Main Authors: Dovmark, TH, Hulikova, A, Niederer, SA, Vaughan-Jones, RD, Swietach, P
Format: Journal article
Published: Federation of American Society of Experimental Biology 2017