Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR

OBJECTIVES:To enhance detection of the products of hyperpolarized [2-13C]dihydroxyacetone metabolism for assessment of three metabolic pathways in the liver in vivo. Hyperpolarized [2-13C]DHAc emerged as a promising substrate to follow gluconeogenesis, glycolysis and the glycerol pathways. However,...

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Бібліографічні деталі
Автори: Marco-Rius, I, Wright, AJ, Hu, D-E, Savic, D, Miller, JJ, Timm, KN, Tyler, D, Brindle, KM, Comment, A
Формат: Journal article
Мова:English
Опубліковано: Springer 2020