Proteome-wide analysis of HIV-specific naive and memory CD4(+) T cells in unexposed blood donors.

The preexisting HIV-1-specific T cell repertoire must influence both the immunodominance of T cells after infection and immunogenicity of vaccines. We directly compared two methods for measuring the preexisting CD4(+) T cell repertoire in healthy HIV-1-negative volunteers, the HLA-peptide tetramer e...

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Bibliographic Details
Main Authors: Campion, S, Brodie, T, Fischer, W, Korber, B, Rossetti, A, Goonetilleke, N, Mcmichael, A, Sallusto, F
Format: Journal article
Language:English
Published: Rockefeller University Press 2014