Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis.

The major known genetic risk factors in multiple sclerosis reside in the major histocompatibility complex (MHC) region. Although there is strong evidence implicating MHC class II alleles and CD4(+) T cells in multiple sclerosis pathogenesis, possible contributions from MHC class I genes and CD8(+) T...

Descripció completa

Dades bibliogràfiques
Autors principals:	Friese, M, Jakobsen, K, Friis, L, Etzensperger, R, Craner, M, McMahon, R, Jensen, LT, Huygelen, V, Jones, E, Bell, J, Fugger, L
Format:	Journal article
Idioma:	English
Publicat:	2008

Ítems similars

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis
per: McMahon, R, et al.
Publicat: (2011)

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis.
per: McMahon, R, et al.
Publicat: (2011)

Autoreactive CD8+ T cells in multiple sclerosis: A new target for therapy?
per: Friese, M, et al.
Publicat: (2005)

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?
per: Friese, M, et al.
Publicat: (2005)

Dissection of the multiple sclerosis associated DR2 haplotype.
per: Etzensperger, R, et al.
Publicat: (2008)

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model
per: Vergo, S, et al.
Publicat: (2011)

Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.
per: Vergo, S, et al.
Publicat: (2011)

Acid sensing ion channel 1 contributes to axonal degeneration in autoimmune CNS inflammation and provides a novel target for neuroprotection in multiple sclerosis
per: Craner, M, et al.
Publicat: (2008)

The immunology of multiple sclerosis
per: Attfield, KE, et al.
Publicat: (2022)

Joint-specific and systemic autoreactivity in the development of inflammatory arthritis.
per: Fugger, L
Publicat: (2000)

IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain.
per: Tzartos, J, et al.
Publicat: (2011)

Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.
per: Friese, M, et al.
Publicat: (2007)

Misfiring in multiple sclerosis: cerebellar channelopathy, a potential novel target?
per: Craner, M, et al.
Publicat: (2012)

From genes to function: the next challenge to understanding multiple sclerosis
per: Fugger, L, et al.
Publicat: (2009)

From genes to function: the next challenge to understanding multiple sclerosis.
per: Fugger, L, et al.
Publicat: (2009)

T cells and microglia as drivers of multiple sclerosis pathology.
per: Friese, M, et al.
Publicat: (2007)

T cells and microglia as drivers of multiple sclerosis pathology
per: Friese, M, et al.
Publicat: (2007)

Pathogenic CD8(+) T cells in multiple sclerosis.
per: Friese, M, et al.
Publicat: (2009)

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis.
per: Tzartos, J, et al.
Publicat: (2008)

Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target
per: Rongzeng Liu, et al.
Publicat: (2022-09-01)

The value of animal models for drug development in multiple sclerosis
per: Friese, M, et al.
Publicat: (2006)

The value of animal models for drug development in multiple sclerosis.
per: Friese, M, et al.
Publicat: (2006)

Multiple sclerosis: MHC associations and therapeutic implications.
per: Holmes, S, et al.
Publicat: (2005)

Autoreactive TCD8+ lymphocytes in patients with chronic myeloid leukemia in association with HLA and adenovirus infection
per: Sergio E. Rivera-Pirela, et al.
Publicat: (2016-05-01)

Humanized mouse models for organ-specific autoimmune diseases.
per: Friese, M, et al.
Publicat: (2006)

A molecule basis for the HLA association in rheumatoid arthritis.
per: Andersson, E, et al.
Publicat: (2000)

Axonal injury in reverse.
per: Craner, M, et al.
Publicat: (2011)

Interleukin-17 expression in multiple sclerosis
per: Tzartos, J, et al.
Publicat: (2006)

Synthetic peptides that inhibit binding of the myelin basic protein 85-99 epitope to multiple sclerosis-associated HLA-DR2 molecules and MBP-specific T-cell responses.
per: Fridkis-Hareli, M, et al.
Publicat: (2001)

Sustained effects on immune cell subsets and autoreactivity in multiple sclerosis patients treated with oral cladribine
per: Rikke Holm Hansen, et al.
Publicat: (2024-02-01)

HLA variation and disease
per: Dendrou, C, et al.
Publicat: (2018)

MHC II molecules in inflammatory diseases: interplay of qualities and quantities.
per: Friese, M, et al.
Publicat: (2005)

NK cell autoreactivity and autoimmune diseases
per: Alessandro ePoggi, et al.
Publicat: (2014-02-01)

Identification of autoreactive B cells with labeled nucleosomes
per: Vincent Gies, et al.
Publicat: (2017-04-01)

T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides (DOI:10.1016/j.immuni.2009.01.009)
per: Harkiolaki, M, et al.
Publicat: (2009)

T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.
per: Harkiolaki, M, et al.
Publicat: (2009)

T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides (vol 30, pg 348, 2009)
per: Harkiolaki, M, et al.
Publicat: (2009)

A clinical conundrum: the detrimental effect of TNF antagonists in multiple sclerosis.
per: Dendrou, C, et al.
Publicat: (2013)

Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice.
per: Kort, J, et al.
Publicat: (2006)

Using HLA DRB1*1501 transgenic mice to study the HLA-linked autoimmune Goodpasture's disease
per: Ooi, J, et al.
Publicat: (2008)