Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.

During gastrulation, cell types from all three germ layers are specified and the basic body plan is established 1 . However, molecular analysis of this key developmental stage has been hampered by limited cell numbers and a paucity of markers. Single-cell RNA sequencing circumvents these problems, b...

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Bibliographic Details
Main Authors: Ibarra-Soria, X, Jawaid, W, Pijuan-Sala, B, Ladopoulos, V, Scialdone, A, Jörg, D, Tyser, R, Calero-Nieto, F, Mulas, C, Nichols, J, Vallier, L, Srinivas, S, Simons, B, Göttgens, B, Marioni, J
Format: Journal article
Language:English
Published: Nature Publishing Group 2018