Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.

The adaptation of animals to oxygen availability is mediated by a transcription factor termed hypoxia-inducible factor (HIF). HIF is an alpha (alpha)/beta (beta) heterodimer that binds hypoxia response elements (HREs) of target genes, including some of medicinal importance, such as erythropoietin (E...

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Váldodahkkit: Hewitson, K, Schofield, C, Ratcliffe, P
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2007