Real-time surface-enhanced Raman spectroscopy monitoring of surface pH during electrochemical melting of double-stranded DNA.

The application of a negative potential ramp at a double-stranded DNA (dsDNA) functionalized electrode surface results in the gradual denaturation of the DNA in a process known as electrochemical melting. The underlying physical chemistry behind electrochemically driven DNA denaturation is not well...

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Bibliographic Details
Main Authors: Johnson, R, Richardson, J, Brown, T, Bartlett, P
Format: Journal article
Language:English
Published: 2012