Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms.

Degradation of the elastic media is a hallmark of abdominal aortic aneurysms (AAAs). We examined the expression of 2 elastolytic matrix metalloproteinases (MMPs), MMP-2 and MMP-9, in AAA aortic tissues compared with those from atherosclerotic occlusive disease (AOD) and nondiseased control tissues....

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Bibliographic Details
Main Authors: Davis, V, Persidskaia, R, Baca-Regen, L, Itoh, Y, Nagase, H, Persidsky, Y, Ghorpade, A, Baxter, B
Format: Journal article
Language:English
Published: 1998