Calculating polygenic risk scores (PRS) in UK Biobank: A practical guide for epidemiologists

A polygenic risk score estimates the genetic risk of an individual for some disease or trait, calculated by aggregating the effect of many common variants associated with the condition. With the increasing availability of genetic data in large cohort studies such as the UK Biobank, inclusion of this...

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Bibliographic Details
Main Authors: Collister, JA, Liu, X, Clifton, L
Format: Journal article
Language:English
Published: Frontiers Media 2022