Screening blockers against a potassium channel with a droplet interface bilayer array.

Droplet interface bilayers (DIBs) form between two lipid monolayer-encased aqueous droplets submerged in oil. Both major structural classes of membrane proteins, alpha-helix bundles and beta barrels, represented by channels and pores, respectively, spontaneously insert into DIBs when freshly express...

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Détails bibliographiques
Auteurs principaux: Syeda, R, Holden, M, Hwang, W, Bayley, H
Format: Journal article
Langue:English
Publié: 2008