Screening blockers against a potassium channel with a droplet interface bilayer array.
Droplet interface bilayers (DIBs) form between two lipid monolayer-encased aqueous droplets submerged in oil. Both major structural classes of membrane proteins, alpha-helix bundles and beta barrels, represented by channels and pores, respectively, spontaneously insert into DIBs when freshly express...
Main Authors: | , , , |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2008
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