High-dose mefloquine in the treatment of multidrug-resistant falciparum malaria.

The therapeutic efficacy and toxicity of a high-dose (25 mg/kg) mefloquine regimen (M25) and the currently recommended regimen of 15 mg/kg (M15) were compared in 199 patients with acute falciparum malaria in an area with deteriorating multidrug resistance on the Thai-Burmese border. The clinical and...

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Detalhes bibliográficos
Main Authors: ter Kuile, F, Nosten, F, Thieren, M, Luxemburger, C, Edstein, MD, Chongsuphajaisiddhi, T, Phaipun, L, Webster, H, White, N
Formato: Journal article
Idioma:English
Publicado em: 1992