CXCR6 is a marker for protective antigen-specific cells in the lungs after intranasal immunization against Mycobacterium tuberculosis.

Convincing correlates of protective immunity against tuberculosis have been elusive. In BALB/c mice, intranasal immunization with a replication-deficient recombinant adenovirus expressing Mycobacterium tuberculosis antigen 85A (adenovirus-85A) induces protective lower respiratory tract immunity agai...

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Bibliographic Details
Main Authors: Lee, L, Ronan, E, de Lara, C, Franken, K, Ottenhoff, T, Tchilian, E, Beverley, P
Format: Journal article
Language:English
Published: 2011