Antibody side chain conformations are position-dependent

Side chain prediction is an integral component of computational antibody design and structure prediction. Current antibody modelling tools use backbone-dependent rotamer libraries with conformations taken from general proteins. Here we present our antibody-specific rotamer library, where rotamers ar...

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Bibliographic Details
Main Authors: Leem, J, Georges, G, Shi, J, Deane, C
Format: Journal article
Language:English
Published: Wiley 2018