Low-energy electron holography imaging of conformational variability of single-antibody molecules from electrospray ion beam deposition

Imaging of proteins at the single-molecule level can reveal conformational variability, which is essential for the understanding of biomolecules. To this end, a biologically relevant state of the sample must be retained during both sample preparation and imaging. Native electrospray ionization (ESI)...

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Bibliographic Details
Main Authors: Ochner, H, Szilagyi, S, Abb, S, Gault, J, Robinson, CV, Malavolti, L, Rauschenbach, S, Kern, K
Format: Journal article
Language:English
Published: National Academy of Sciences 2021