Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

CD8 T cells lose the capacity to control HIV infection, but the extent of the impairment of CD8 T-cell functions and the mechanisms that underlie it remain controversial. Here we report an extensive ex vivo analysis of HIV-specific CD8 T cells, covering the expression of 16 different molecules invol...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Ribeiro-dos-Santos, P, Turnbull, E, Monteiro, M, Legrand, A, Conrod, K, Baalwa, J, Pellegrino, P, Shaw, G, Williams, I, Borrow, P, Rocha, B
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2012