Stochasticity and the molecular mechanisms of induced pluripotency

The generation of induced pluripotent stem cells from adult somatic cells by ectopic expression of key transcription factors holds significant medical promise. However, current techniques for inducing pluripotency rely on viral infection and are therefore not, at present, viable within a clinical se...

Full description

Bibliographic Details
Main Authors: Macarthur, B, Please, C, Oreffo, R
Format: Journal article
Language:English
Published: Public Library of Science 2008