TRAM, LAG1 and CLN8: members of a novel family of lipid-sensing domains?
A family of membrane-associated proteins related to yeast Lag1p and mammalian TRAM has been identified. The family includes the protein product of CLN8, a gene mutated in progressive epilepsy with mental retardation. Mouse CLN8 is also mutated in the mnd/mnd mouse, a model for neuronal ceroid lipofu...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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