Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.

BACKGROUND: Tuberculosis (TB) remains a global health problem, with vaccination likely to be a necessary part of a successful control strategy. Results of the first Phase 2b efficacy trial of a candidate vaccine, MVA85A, evaluated in BCG-vaccinated infants were published last year. Although no impro...

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Main Authors: Matsumiya, M, Harris, SA, Satti, I, Stockdale, L, Tanner, R, O'Shea, M, Tameris, M, Mahomed, H, Hatherill, M, Scriba, T, Hanekom, W, Mcshane, H, Fletcher, H
格式: Journal article
語言:English
出版: BioMed Central 2014
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