Assessing the effect of anesthetic gas mixtures on hyperpolarized 13C pyruvate metabolism in the rat brain

Purpose To determine the effect of altering anesthetic oxygen protocols on measurements of cerebral perfusion and metabolism in the rodent brain. Methods Seven rats were anesthetized and underwent serial MRI scans with hyperpolarized [1–13C]pyruvate and perfusion weighted imaging. The anesthetic ca...

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Bibliographic Details
Main Authors: Healicon, R, Rooney, C, Ball, V, Shinozaki, A, Miller, J, Smart, S, Radford-Smith, D, Anthony, D, Tyler, D, Grist, J
Format: Journal article
Language:English
Published: Wiley 2022