Metampicillin is a cyclic aminal produced by reaction of ampicillin with formaldehyde

Metampicillin is a β-lactam antibiotic that is prepared by the reaction of ampicillin with formaldehyde. Although metampicillin has been studied for treatment of infections in animals and humans, its structure has been unclear. We report NMR studies revealing that metampicillin contains a formaldehy...

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Bibliographic Details
Main Authors: Reinbold, R, John, T, Spingardi, P, Kawamura, A, Schofield, C, Hopkinson, R
Format: Journal article
Language:English
Published: Nature Research 2020