Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis

Fast synaptic inhibition in the nervous system depends on the transmembrane flux of Cl- ions based on the neuronal Cl- driving force. Established theories regarding the determinants of Cl- driving force have recently been questioned. Here we present biophysical models of Cl- homeostasis using the pu...

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Bibliographic Details
Main Authors: Düsterwald, K, Currin, C, Burman, R, Akerman, C, Kay, A, Raimondo, J
Format: Journal article
Published: eLife Sciences Publications 2018