NK1 receptor antagonism and emotional processing in healthy volunteers.

The neurokinin-1 (NK(1)) receptor antagonist, aprepitant, showed activity in several animal models of depression; however, its efficacy in clinical trials was disappointing. There is little knowledge of the role of NK(1) receptors in human emotional behaviour to help explain this discrepancy. The ai...

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Bibliographic Details
Main Authors: Chandra, P, Hafizi, S, Massey-Chase, R, Goodwin, G, Cowen, P, Harmer, C
Format: Journal article
Language:English
Published: 2010