NK1 receptor antagonism and emotional processing in healthy volunteers.

The neurokinin-1 (NK(1)) receptor antagonist, aprepitant, showed activity in several animal models of depression; however, its efficacy in clinical trials was disappointing. There is little knowledge of the role of NK(1) receptors in human emotional behaviour to help explain this discrepancy. The ai...

Полное описание

Библиографические подробности
Главные авторы: Chandra, P, Hafizi, S, Massey-Chase, R, Goodwin, G, Cowen, P, Harmer, C
Формат: Journal article
Язык:English
Опубликовано: 2010