NK1 receptor antagonism and emotional processing in healthy volunteers.
The neurokinin-1 (NK(1)) receptor antagonist, aprepitant, showed activity in several animal models of depression; however, its efficacy in clinical trials was disappointing. There is little knowledge of the role of NK(1) receptors in human emotional behaviour to help explain this discrepancy. The ai...
Main Authors: | Chandra, P, Hafizi, S, Massey-Chase, R, Goodwin, G, Cowen, P, Harmer, C |
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Format: | Journal article |
Language: | English |
Published: |
2010
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