DehydromicroscleroderminB and MicroscleroderminJ: Total synthesis and structural revision

The total synthesis of dehydromicroscleroderminB and microscleroderminJ is described. Efficient approaches to the unusual amino acids in the target molecules were developed on the basis of a Negishi coupling (for Trp-2-CO2H) and Blaise reaction (for Pyrr). An incorrect assignment of the pyrrolidinon...

Full description

Bibliographic Details
Main Authors: Melikhova, E, Pullin, R, Winter, C, Donohoe, T
Format: Journal article
Language:English
Published: Wiley 2016