ChAd63-MVA-vectored blood-stage Malaria vaccines targeting MSP1 and AMA1: Assessment of efficacy against mosquito bite challenge in humans

ChAd63-MVA-vectored blood-stage Malaria vaccines targeting MSP1 and AMA1: Assessment of efficacy against mosquito bite challenge in humans

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The induction of cellular immunity, in conjunction with antibodies, may be essential for vaccines to protect against blood-stage infection with the human malaria parasite Plasmodium falciparum. We have shown that prime-boost delivery of P. falciparum blood-stage antigens by chimpanzee adenovirus 63...

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Bibliographic Details
Main Authors: Sheehy, S, Duncan, C, Elias, S, Choudhary, P, Biswas, S, Halstead, F, Collins, K, Edwards, N, Douglas, A, Anagnostou, N, Ewer, K, Havelock, T, Mahungu, T, Bliss, C, Miura, K, Poulton, I, Lillie, P, Antrobus, R, Berrie, E, Moyle, S, Gantlett, K, Colloca, S, Cortese, R
Format: Journal article
Published: 2012

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