The role of Topoisomerase II in replication in mammalian cells

<p>Topoisomerase 2α (Topo2α) is an essential protein with DNA decatenating enzymatic properties, indispensable for chromosome decatenation and segregation. It is a target for a plethora of antitumour drugs and Topo2α protein levels have been associated with the success of treatment, but also d...

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Bibliographic Details
Main Author: Muftic, D
Other Authors: Helleday, T
Format: Thesis
Language:English
Published: 2011
Subjects: