The role of Topoisomerase II in replication in mammalian cells
<p>Topoisomerase 2α (Topo2α) is an essential protein with DNA decatenating enzymatic properties, indispensable for chromosome decatenation and segregation. It is a target for a plethora of antitumour drugs and Topo2α protein levels have been associated with the success of treatment, but also d...
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Format: | Thesis |
Language: | English |
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2011
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